On scrutiny of your wife’s horoscope, her 6th, 11th and 12th houses are impotent and that is what she is suffering now. And she will continue to have discomforts on account of this with varying degrees throughout her life. Also she has a strong Pravarjya yoga too.
I think she will have to live this problem. Reciting scriptural verses could ease the intensity of the problems. Read my blog for details of signification of the above houses and remedies.