There is 2-12 Bhakoot dosha and Madhya Nadi dosha. When these two dosha are there marriage should be done with care. As it indicates health problems, problems to children and financial problems. Therefore you should get a complete Graha milan done to see what your stars tell. Do these dosha actually reflect in the horoscope.
You can look at “Horoscope Matching Kundali Milan for detailed Guna and Graha Milan analysis.